Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 1
1983 1
1986 1
1990 1
1992 5
1993 15
1994 24
1995 26
1996 51
1997 58
1998 80
1999 82
2000 85
2001 79
2002 91
2003 99
2004 122
2005 137
2006 152
2007 158
2008 148
2009 150
2010 162
2011 150
2012 174
2013 194
2014 182
2015 167
2016 176
2017 172
2018 141
2019 130
2020 144
2021 138
2022 107
2023 81
2024 39

Text availability

Article attribute

Article type

Publication date

Search Results

3,381 results

Results by year

Filters applied: . Clear all
Page 1
Cargo-specific recruitment in clathrin- and dynamin-independent endocytosis.
Moreno-Layseca P, Jäntti NZ, Godbole R, Sommer C, Jacquemet G, Al-Akhrass H, Conway JRW, Kronqvist P, Kallionpää RE, Oliveira-Ferrer L, Cervero P, Linder S, Aepfelbacher M, Zauber H, Rae J, Parton RG, Disanza A, Scita G, Mayor S, Selbach M, Veltel S, Ivaska J. Moreno-Layseca P, et al. Nat Cell Biol. 2021 Oct;23(10):1073-1084. doi: 10.1038/s41556-021-00767-x. Epub 2021 Oct 6. Nat Cell Biol. 2021. PMID: 34616024 Free article.
Here we identify the actin-binding protein Swiprosin-1 (Swip1, EFHD2) as a cargo-specific adaptor for CG-endocytosis. Swip1 couples active Rab21-associated integrins with key components of the CG-endocytic machinery-Arf1, IRSp53 and actin-and is critical for integri …
Here we identify the actin-binding protein Swiprosin-1 (Swip1, EFHD2) as a cargo-specific adaptor for CG-endocytosis. Swip1 couple …
Toll-like receptor 3 (TLR3) regulation mechanisms and roles in antiviral innate immune responses.
Chen Y, Lin J, Zhao Y, Ma X, Yi H. Chen Y, et al. J Zhejiang Univ Sci B. 2021 Aug 15;22(8):609-632. doi: 10.1631/jzus.B2000808. J Zhejiang Univ Sci B. 2021. PMID: 34414698 Free PMC article. Review.
Toll-like receptor 3 (TLR3) is a member of the TLR family, mediating the transcriptional induction of type I interferons (IFNs), proinflammatory cytokines, and chemokines, thereby collectively establishing an antiviral host response. Studies have shown that unlike other TL …
Toll-like receptor 3 (TLR3) is a member of the TLR family, mediating the transcriptional induction of type I interferons (IFNs), proi …
Co-adaptor driven assembly of a CUL3 E3 ligase complex.
Akopian D, McGourty CA, Rapé M. Akopian D, et al. Mol Cell. 2022 Feb 3;82(3):585-597.e11. doi: 10.1016/j.molcel.2022.01.004. Mol Cell. 2022. PMID: 35120648 Free PMC article.
As the co-adaptor also helps recruit substrates, its role in CRL assembly couples target recognition to ubiquitylation. We propose that regulators dedicated to specific CRLs, such as assembly inhibitors or co-adaptors, cooperate with target-agnostic adapto …
As the co-adaptor also helps recruit substrates, its role in CRL assembly couples target recognition to ubiquitylation. We pro …
Bile Acids Signal via TGR5 to Activate Intestinal Stem Cells and Epithelial Regeneration.
Sorrentino G, Perino A, Yildiz E, El Alam G, Bou Sleiman M, Gioiello A, Pellicciari R, Schoonjans K. Sorrentino G, et al. Gastroenterology. 2020 Sep;159(3):956-968.e8. doi: 10.1053/j.gastro.2020.05.067. Epub 2020 May 30. Gastroenterology. 2020. PMID: 32485177 Free article.
Bile acids (BAs), metabolites in the gut, signal nutrient availability by activating the G protein-coupled bile acid receptor 1 (GPBAR1, also called TGR5). TGR5 is expressed in the intestinal epithelium, but it is not clear how its activation affects ISCs and regeneration …
Bile acids (BAs), metabolites in the gut, signal nutrient availability by activating the G protein-coupled bile acid receptor 1 (GPBA …
SnapShot: β-Arrestin Functions.
Ahn S, Shenoy SK, Luttrell LM, Lefkowitz RJ. Ahn S, et al. Cell. 2020 Sep 3;182(5):1362-1362.e1. doi: 10.1016/j.cell.2020.07.034. Cell. 2020. PMID: 32888497 Free article.
The arrestins are ubiquitously expressed adaptor proteins that orchestrate transmembrane signaling cascades triggered by the 7-transmembrane G protein-coupled receptors. While originally discovered as proteins that block receptor-G protein coupling, arrestins …
The arrestins are ubiquitously expressed adaptor proteins that orchestrate transmembrane signaling cascades triggered by the 7-transm …
Coupling the TCR to downstream signalling pathways: the role of cytoplasmic and transmembrane adaptor proteins.
Marie-Cardine A, Schraven B. Marie-Cardine A, et al. Cell Signal. 1999 Oct;11(10):705-12. doi: 10.1016/s0898-6568(99)00047-9. Cell Signal. 1999. PMID: 10574324 Review.
One of the first detectable consequences of TCR triggering is the activation of cytoplasmic protein kinases which, through phosphorylation of specific substrates, couple the TCR to downstream signalling cascades. Although it is well established that activation of the Ras- …
One of the first detectable consequences of TCR triggering is the activation of cytoplasmic protein kinases which, through phosphorylation o …
Regulation of long-distance transport of mitochondria along microtubules.
Melkov A, Abdu U. Melkov A, et al. Cell Mol Life Sci. 2018 Jan;75(2):163-176. doi: 10.1007/s00018-017-2590-1. Epub 2017 Jul 12. Cell Mol Life Sci. 2018. PMID: 28702760 Free PMC article. Review.
Two adaptor proteins are involved directly in mitochondria-motor coupling, namely Milton known also as TRAK, which is the motor adaptor, and Miro, which is the mitochondrial protein. Here, we discuss the active mitochondria transport process, as well as motor …
Two adaptor proteins are involved directly in mitochondria-motor coupling, namely Milton known also as TRAK, which is the moto …
Unraveling the intricate cargo-BBSome coupling mechanism at the ciliary tip.
Liu YX, Li WJ, Zhang RK, Sun SN, Fan ZC. Liu YX, et al. Proc Natl Acad Sci U S A. 2023 Mar 28;120(13):e2218819120. doi: 10.1073/pnas.2218819120. Epub 2023 Mar 21. Proc Natl Acad Sci U S A. 2023. PMID: 36943875 Free PMC article.
The Arf-like 13 (ARL13) small GTPase resembles ARL6/BBS3 in facilitating these signaling cargoes to couple with the BBSome at the ciliary tip prior to loading onto retrograde IFT trains for transporting towards the ciliary base, while the molecular basis for how this intri …
The Arf-like 13 (ARL13) small GTPase resembles ARL6/BBS3 in facilitating these signaling cargoes to couple with the BBSome at the cil …
Conformational regulation of AP1 and AP2 clathrin adaptor complexes.
Beacham GM, Partlow EA, Hollopeter G. Beacham GM, et al. Traffic. 2019 Oct;20(10):741-751. doi: 10.1111/tra.12677. Epub 2019 Aug 6. Traffic. 2019. PMID: 31313456 Free PMC article. Review.
Heterotetrameric clathrin adaptor protein complexes (APs) orchestrate the formation of coated vesicles for transport among organelles of the cell periphery. ...At their respective membranes, AP1 and AP2 bind the cytoplasmic tails of transmembrane protein cargo and clathrin …
Heterotetrameric clathrin adaptor protein complexes (APs) orchestrate the formation of coated vesicles for transport among organelles …
Coupling transcription to RNA processing via the p68 DEAD box RNA helicase androgen receptor co-activator in prostate cancer.
Clark EL, Fuller-Pace FV, Elliott DJ, Robson CN. Clark EL, et al. Biochem Soc Trans. 2008 Jun;36(Pt 3):546-7. doi: 10.1042/BST0360546. Biochem Soc Trans. 2008. PMID: 18482004 Review.
Current models of gene expression indicate that transcription and RNA processing are tightly coupled. In this review, we discuss how the ATP-dependent DEAD box RNA helicase p68, which has established roles in transcription and RNA processing, may function as an 'adaptor …
Current models of gene expression indicate that transcription and RNA processing are tightly coupled. In this review, we discuss how …
3,381 results